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Filtered Search Results
Apexbio Technology LLC Perindopril 82834-16-0 250mg
Perindopril (CAS 82834-16-0) is an inhibitor of angiotensin I-converting enzyme (ACE) widely used in biomedical research By blocking ACE activity Perindopril suppresses the formation of angiotensin II a peptide involved in vasoconstriction and angiogenesis In cancer studies Perindopril has demonstrated the ability to inhibit tumor growth and angiogenesis in head and neck squamous cell carcinoma models While it does not significantly affect cell proliferation in vitro it reduces VEGF mRNA expression and promoter activity at concentrations as low as 1 M In vivo Perindopril has been shown to suppress tumor growth and lower blood pressure without altering heart rate supporting its application in oncology and cardiovascular research
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Medchemexpress LLC 2'-O-Methylguanosine | 2140-71-8 | 99.8% | 297.27 | 250 MG
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2'-O-Methylguanosine is a modified nucleoside produced in tRNAs by the action of tRNA guanosine-2'-O-methyltransferase. It results in apoptotic changes of cells. For research use only; not sold to patients.
- Modified nucleoside produced in tRNAs
- Induces apoptotic changes in cells
- Can be isolated from the culture supernatant of CD57⁺HLA-DRbright natural suppressor cell (57.DR-NS)
- Induces apoptosis in Molt4 cells at 7 μg/mL for 72 h
- Inhibits the activity of RNA-dependent RNA polymerase after nucleotide incorporation by hindering translocation
- Protects coronavirus RNA from degradation by host nucleases
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![Medchemexpress LLC N-Succinimidyl 4-[4-maleimidophenyl]butyrate | 79886-55-8 | 98.0% | 356.33 | 250 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000453332-logo.png-250.jpg){kind=logo}
Medchemexpress LLC N-Succinimidyl 4-[4-maleimidophenyl]butyrate | 79886-55-8 | 98.0% | 356.33 | 250 MG
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N-Succinimidyl 4-[4-maleimidophenyl]butyrate is a chemical compound that functions as a crosslinking agent. It is intended for research use only and has not been fully validated for medical applications.
- Molecular formula: C18H16N2O6
- Target: DNA alkylator/crosslinker
- Pathway: Cell cycle/DNA damage
- Storage conditions: -20°C, stored under nitrogen, away from moisture. In solvent: -80°C for 6 months; -20°C for 1 month
- Solubility (in vitro): DMSO: 100 mg/mL (280.64 mM)
- Appearance: White to off-white solid
- Melting point: 130-131 °C
- Boiling point: 551.1±60.0 °C at 760 mmHg
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Medchemexpress LLC 7,12-DMBA; 7,12-Dimethylbenzanthracene | 57-97-6 | 99.9% | 256.35 | 250 MG
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DMBA (7,12-Dimethylbenzanthracene) is a polycyclic aromatic hydrocarbon (PAH) known for its carcinogenic activity. It is widely utilized in research to induce tumor formation in various rodent models, serving as a key tool in cancer studies.
- Carcinogenic polycyclic aromatic hydrocarbon
- Induces tumor formation in rodent models
- Targets c-Myc
- Inhibits apoptosis pathway
- Solid, light yellow to yellow appearance
- Powder storage: -20°C for 3 years; 4°C for 2 years
- Solvent storage: -80°C for 6 months; -20°C for 1 month
- Solubility in acetone, DMSO, ethanol, and corn oil
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Medchemexpress LLC Suberoyl bis-hydroxamic acid | 38937-66-5 | 95.0% | 204.22 | 250 MG
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Suberoyl bis-hydroxamic acid is a competitive and cell-permeable HDAC1 and HDAC3 inhibitor. It renders MM cells susceptible to apoptosis, facilitating mitochondrial apoptotic pathways. This product can be used for the study of medullary thyroid carcinoma (MTC).
- Competitive and cell-permeable HDAC1 and HDAC3 inhibitor
- Renders MM cells susceptible to apoptosis
- Facilitates mitochondrial apoptotic pathways
- Suitable for the study of medullary thyroid carcinoma (MTC)
- Appears as a white to off-white solid
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Medchemexpress LLC 3-Pyridinecarboxylic acid, 2-methyl-, ethyl ester | 1721-26-2 | 99.4% | 165.19 | 5 G
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Ethyl 2-methylnicotinate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It has been utilized in the preparation of amino esters such as ethyl 2(piperidinylaminomethyl)benzoate, ethyl 2-(N-benzyl-N-methylaminomethyl)benzoate, and ethyl 2-(diethylaminomethyl)benzoate.
- Biochemical reagent for life science research.
- Can be used as a biological material or organic compound.
- Suitable for the preparation of amino esters.
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Medchemexpress LLC 2-Ethyl-6-methylaniline-d13 | 1219794-93-0 | 98.6% | 148.29 | 10 MG
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2-Ethyl-6-methylaniline-d13 is the deuterium labeled 2-Ethyl-6-methylaniline. It is designed for research use only and not for patient use. This compound serves as a tracer and an internal standard for quantitative analysis through techniques like NMR, GC-MS, or LC-MS. Incorporating stable heavy isotopes into drug molecules, particularly deuterium, offers the potential to influence pharmacokinetic and metabolic profiles of drugs during development.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeling can impact pharmacokinetic and metabolic profiles of pharmaceuticals
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Medchemexpress LLC Pomalidomide 4'-alkylC5-acid | 2225940-49-6 | 98.8% | 250 MG
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Pomalidomide 4'-alkylC5-acid is an E3 ligase ligand-linker conjugate. It contains a cereblon (CRBN) ligand, which is Pomalidomide based, and a linker. This compound can be utilized in the synthesis of PROTAC (Proteolysis Targeting Chimeras). PROTACs are composed of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. These molecules function by harnessing the intracellular ubiquitin-proteasome system to achieve the selective degradation of target proteins.
- Can be utilized in the synthesis of PROTAC
- Contains a cereblon (CRBN) ligand
- Contains a linker
- Targets an E3 ubiquitin ligase
- Targets the protein of interest
- Harnesses the intracellular ubiquitin-proteasome system
- Achieves selective degradation of target proteins
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Medchemexpress LLC Methyl 2-aminoisobutyrate hydrochloride | 15028-41-8 | 153.61 | 250 G
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Methyl 2-aminoisobutyrate hydrochloride is a biochemical reagent suitable for various life science related research. It can be utilized as a biological material or an organic compound. This product is intended for research use only.
- Biochemical reagent for life science research
- Can be used as a biological material
- Can be used as an organic compound
- Appearance: Solid, white to off-white
- Storage: -20°C, sealed, away from moisture
- Storage in solvent: -80°C for 6 months; -20°C for 1 month (sealed, away from moisture)
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Aobchem Ethyl 2 5-dibromo-3-pyridinecarboxylate | ≥97% | CAS 1214375-74-2 | C8H7Br2NO2 | 500mg
Ethyl 2 5-dibromo-3-pyridinecarboxylate | ≥97% | CAS 1214375-74-2 | C8H7Br2NO2 | 500mg
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Medchemexpress LLC 2'-O-methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite | 128219-85-2 | MFCD08062007 | 98.0% | 784.84 | C41H49N6O8P | 250 MG
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2'-O-Methyl-5'-O-dmt-inosine-3'-CE-phosphoramidite is a modified nucleoside phosphoramidite used for incorporation of inosine into oligonucleotides. It features a 2'-O-methyl ribose modification, a 5'-O-dimethoxytrityl protecting group, and a 3'-cyanoethyl phosphoramidite moiety compatible with automated solid-phase synthesis. Intended for research use, it supports generation of modified RNA and probes for biochemical studies.
- Modified nucleoside for incorporation into oligonucleotides.
- 2'-O-methyl modification increases nuclease resistance.
- 5'-O-dimethoxytrityl protection enables stepwise synthesis monitoring.
- 3'-cyanoethyl phosphoramidite suitable for automated solid-phase synthesis.
- High purity suitable for research applications.
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eMolecules 80-48-8 | Methyl 4-methylbenzenesulfonate | Synthonix | MFCD00008417 | 186.230 | C8H10O3S | 95.000 | COS(=O)(=O)c1ccc(C)cc1 | 100g | 810551173
Methyl 4-methylbenzenesulfonate | Synthonix | 80-48-8 | MFCD00008417 | 186.230 | C8H10O3S | 95.000 | COS(=O)(=O)c1ccc(C)cc1 | 100g | 810551173
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eMolecules 4994-86-9 | 4-Chloro-2-methyl-pyrimidine | Oakwood Chemical | MFCD00234069 | 128.560 | C5H5ClN2 | 0.000 | Cc1nccc(Cl)n1 | 1g | 537695490
4-Chloro-2-methyl-pyrimidine | Oakwood Chemical | 4994-86-9 | MFCD00234069 | 128.560 | C5H5ClN2 | 0.000 | Cc1nccc(Cl)n1 | 1g | 537695490
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(C)C | 5g | 480170956](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000224875.jpg-250.jpg)
eMolecules 7449-74-3 | N-Methyl-N-trimethylsilylacetamide | Oakwood Chemicals | MFCD00040758 | 145.277 | C6H15NOSi | 97.000 | CN(C(C)=O)[Si](C)(C)C | 5g | 480170956
N-Methyl-N-trimethylsilylacetamide | Oakwood Chemicals | 7449-74-3 | MFCD00040758 | 145.277 | C6H15NOSi | 97.000 | CN(C(C)=O)[Si](C)(C)C | 5g | 480170956
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Medchemexpress LLC Methyl prolinate hydrochloride | 2133-40-6 | >=97.0% | C6H12ClNO2 | 100 G
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Methyl prolinate hydrochloride is a biochemical reagent designed for life science research. This organic compound is suitable for use as a biological material in various laboratory applications.
- Biochemical reagent
- Can be used as a biological material
- Can be used as an organic compound
- Suitable for life science related research
- Molecular weight: 165.62
- Appearance: White to off-white solid
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